Hypopigmented macules of the limbs in two sisters: report on familial Bier spots

Hypopigmented macules of the limbs in two sisters: report on familial Bier spots*

Bier spots are asymptomatic, small, irregular, hypopigmented macules characterized by a normal histological appearance, which are usually found on the arms and legs of young adults. We describe the simultaneous presence of Bier spots in two siblings. This finding is unusual since, to the best of our knowledge, concurrent familial cases have never been reported in the literature.

[Focal hypopigmented macules].

A 29-year-old man with a past history of appendectomy and morbid obesity, was seen for asymptomatic lesions that had appeared 7 to 8 years earlier on the hands and forearms. Multiple hypopigmented macules of 4 to 6 mm in diameter, with poorly defined borders and with surrounding erythema, were observed on the external aspect of both forearms and, more intensely, on the dorsum of the hands (Figu...

Bier spots.

Bier’s spots with onset in childhood*

Bier spots are small, irregular, hypopigmented macules that are usually found on the arms and legs. The macules disappear when the limb is raised. Bier spots have been reported in association with a number of conditions but there is no consistent association to specific desease. Although they usually affect young adults, we report a case of Bier spots that began in childhood. As an asymptomatic...

Bier Spots with Characteristic Clinic Presentation: Case Report

Bier spots (BS) were first described in 1898 by Bier and detailed research by Lewis in 1927 [1,2]. There is no certain information about prevalence [2]. It is usually seen in people 20 to 40 years old young adults and is more common in women than man. Pediatric cases were reported [2]. BS are also called physiologic anemic macules, angiospastic macules, exaggerated physiologic speckled mottling...